摘要:
Ischemia and reperfusion injury (IRI), an inevitable component in organ transplantation, contributes to inferior graft survival, compromised organ quality and limitations in organ availability. The heart is most vulnerable to IRI and tolerated ischemic times are very short. We present an entire novel heart transplant procedure during which the donor heart was continuously perfused, oxygenated at normothermia and transplanted while beating. The dynamic electrocardiogram and echocardiogram indicated an absence of ischemic injury and excellent function of the donor heart during the entire procedure. This ischemia-free beating heart transplantation (IFBHT) avoids graft IRI. The approach has thus the potential to improve transplant outcome while improving organ utilization.
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来自:
尹美娴
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分类:
医学、药学
>>
临床医学
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引用:
ChinaXiv:202110.00002
(或此版本
ChinaXiv:202110.00002V1)
doi:10.12074/202110.00002
CSTR:32003.36.ChinaXiv.202110.00002.V1
- 推荐引用方式:
Yin Shengli,Rong Jian,Chen Yinghua,Cao Lu,Liu Yunqi,Mo Shaoyan,Li Hanzhao,Jiang Nan,Xiong Mai,Shi Han,Wang Tielong,Shi Yongxu,Zhu Yanlin,Liang Mengya,Xiong Wei,Chen Yili,Xu Guixing,Chen Xiaoxiang,Chen Xiaojun,Yin Meixian,Tang Baiyun,Gong Fengqiu,Huang Wenqi,Dong Yugang,Bj?rn Nashan,Stefan G Tullius,Guo Zhiyong,Wu Zhongkai,He Xiaoshun.(2021).Transplantation of a Beating Heart: A First in Human.中国科学院科技论文预发布平台.[ChinaXiv:202110.00002]
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