Subjects: Psychology >> Social Psychology submitted time 2023-03-28 Cooperative journals: 《心理科学进展》
Abstract： The neuropeptide, oxytocin (OT) has been established to play an important role in modulating social behavior and emotional processing which are of fundamental importance in our everyday life. Animal and human studies using multi-modal approaches have provided converging evidence for an important modulatory effect of exogenously administered OT on learning and memory. This effect of exogenous OT may be mediated via its receptors which are extensively distributed in key learning and memory brain networks, notably the dopamine reward pathway and limbic system. Whether OT has a facilitatory or inhibitory modulatory effect on learning and memory can be influenced by experimental paradigms and stimulus materials as well as where and when it is administered and at what dose. Future studies need to combine the respective advantages of animal models and human research and to employ standardized experimental protocols and treatment procedures to overcome current limitations in this field. Further research is also required to explore the therapeutic potential of OT for learning and memory dysfunction in psychiatric disorders.
Subjects: Psychology >> Cognitive Psychology submitted time 2017-12-29
Abstract： Numerous evidence has indicated that the high-level cognitive functions are not carried out by isolated operation of single brain area, but through the dynamic interactions between multiple large-scale brain networks. Among them, frontoparietal control network plays a pivotal gate-keeping role in goal-directed cognition, modulating the dynamic balance between the dorsal attention network and default network. Dorsal attention network is mainly responsible for the external top-down attention-oriented and visual space perception. The default network is considered to support internally oriented and self-referential mental processes. By selectively cooperating with the default network or dorsal attention network according to the attentional demands of the task, the frontoparietal control network may serve as a cortical mediator linking the two networks to support adaptive cognitive processes. Regarding these three large-scale brain networks, there are still some debates in the nodes (regions), the functional characterization and interactive relationship. Future research needs to further explore the functional roles of the subsystems within each network, and use the effective connectivity method to examine the direction and dynamics of the information transmission within and between networks.
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